Journal of Pediatric Health Care
Volume 19, Issue 6 , Pages 386-391 , November 2005

Omalizumab: A Steroid-sparing Option for Improving Pediatric Asthma Management?

  • Leslie A. Briars, PharmD

      Affiliations

    • Corresponding Author InformationReprint requests: Leslie Briars, PharmD, College of Pharmacy, The University of Illinois Medical Center at Chicago, 833 South Wood Street (M/C 886), Chicago, IL 60612
    • ,
  • Anyzeila Diaz

References 

  1. Arshad SH , Kurukulaaratchy RJ , Fenn M , Matthews S . Early life risk factors for current wheeze, asthma, and bronchial hyperresponsiveness at 10 years of age . Chest . 2005;127:502–508
  2. Berger W , Gupta N , McAlary M , Fowler-Taylor A . Evaluation of long-term safety of the anti-IgE antibody, omalizumab, in children with allergic asthma . Annals of Allergy Asthma and Immunology . 2003;91:182–188
  3. Centers for Disease Control . QuickStats (Percentage of children aged < 18 years who have ever had asthma diagnosed, by age group—United States, 2003) . Morbidity and Mortality Weekly Report . 2005;54:412
  4. Holgate S , Casale T , Wenzel S , Bousquet J , Deniz Y , Reisner C . The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation . Journal of Allergy and Clinical Immunology . 2005;115:459–465
  5. Lemanske RF , Nayak A , McAlary M , Everhard F , Fowler-Taylor A , Gupta N . Omalizumab improves asthma-related quality of life in children with allergic asthma . Pediatrics . 2002;110:e55
  6. Milgrom H, Berger W, Nayak A, Gupta N, Pollard S, McAlary M, et al. Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab) . Pediatrics . 2001;108:e36
  7. National Heart, Lung, and Blood Institute and the National Asthma Education and Prevention Program . Guidelines for the diagnosis and management of asthma . Bethesda, MD: U.S. Department of Health and Human Services; 2002; Update on selected topics, Pub. No. 02-5074
  8. Product Information . San Francisco, CA: Xolair. Genentech, Inc; 2005; Novartis Pharmaceuticals Corporation, East Hanover, NJ
  9. Rosenwasser LJ , Nash DB . Incorporating omalizumab into asthma treatment guidelines (Consensus panel recommendations) . Pharmacy and Therapeutics . 2003;28:400–410
  10. Taussig LM , Wright AL , Holberg CJ , Halonen M , Morgan WJ , Martinez FD . Tucson children’s respiratory study (1980 to present) . Journal of Allergy and Clinical Immunology . 2003;111:661–675

PII: S0891-5245(05)00305-6

doi: 10.1016/j.pedhc.2005.09.001

Journal of Pediatric Health Care
Volume 19, Issue 6 , Pages 386-391 , November 2005

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